PhD candidate - Research Project Ferroptose

Are you passionate about science, full of ideas and innovative potential that drive change, and enjoy working in an international, fast-paced environment? Are you motivated by the societal impact of research and seek an opportunity to play an instrumental part in understanding the underlying molecular pathogenic mechanisms of disease? Then the Institute of Lung Health and Immunity (LHI) at Helmholtz Munich, Germany, is the ideal environment for you!

PhD candidate - Research Project Ferroptose

Full time
Neuherberg near Munich
PhD

Your mission

You will utilize cutting-edge technologies established in the lab with ex-vivo and in vivo mouse models to examine the possible role of ferroptosis in the early Ischemia-reperfusion (IR) event after Lung transplantation (LTx). Unfortunately, lung transplantation displays the worst long-term survival in all solid organ transplantations. Although surgical technique, donor selection, lung preservation, and immunosuppressive therapies have been advanced, the median survival after lung transplantation has increased only slightly, to just 6.7 years in adults. With this project, you will help understand the role of ferroptotic cell death in Ischemia-reperfusion injury.

Your tasks will include:

• Analysis of preclinical animal models of lung disease
• Analysis of human samples (blood, BALF, tissue biopsies)
• Histopathology analysis and imaging
• In vitro and Ex vivo cell culture screening assays
• Project management (data analysis, quality assurance and monitoring, writing of reports and publications)

Your qualifications

• University degree (M.Sc.) in Immunology, Biology, Molecular Medicine or similar field with outstanding results
• Previous experience in cellular and molecular techniques (cell culture, qPCR and Western blot, ELISA, Immunohistochemistry and Immunofluorescence)
• High motivation, enthusiasm and commitment to science
• Ability to work independently and goal-oriented
• An open and curious mindset and team spirit
• Excellent communication and scientific writing skills in English

Desirable qualifications

• Previous flow cytometry experience advantageous but not crucial

• Previous experience in mouse work is considered a plus

What we offer you

• scientific training at HELENA Graduate School
• work-life balance
• flexible working hours & time off in lieu
• 30 days annual leave
• on-site health management service

• career consultation
• mobile work
• on-site nursery
• company pension scheme
• discounted public transport ticket

Munich, with its numerous lakes and its vicinity to the Alps, is considered to be one of the cities with the best quality of life worldwide. With its first-class universities and world-leading research institutions it offers an intellectually stimulating environment.

This position also provides the opportunity for you to build specialist knowledge and collect significant professional experience, both of which will help advance your scientific career.

Remuneration and social benefits are based on the collective wage agreement for public-sector employees at federal level (EG 13 50% TV EntgO Bund). In addition, there is also the possibility of granting an allowance if the necessary conditions are fulfilled. The position is (initially) limited to three years, but under certain circumstances an extension can be arranged.

To promote diversity, we welcome applications from talented people regardless of gender, cultural background, nationality, ethnicity, sexual identity, physical abilities, religion and age. Qualified applicants with physical disabilities will be given preference.
If you have obtained a university degree abroad, we require further documents from you regarding the recognition of the degree. Please request the recognition as early as possible.

Interested?
If you have further questions, simply contact

Aicha Jeridi
aicha.jeridi@helmholtz-muenchen.de
+49 89 3187 49870,

or Yildirim Ali Önder
oender.yildirim@helmholtz-muenchen.de
+49 89 3187 4037

who will be happy to be of assistance.

Helmholtz Zentrum München
Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH)
Institute of Lung Health and Immunity
Ingolstädter Landstraße 1
85764 Oberschleißheim